Group Tschan

Group Tschan

Publications

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2019

Djavaheri-Mergny, Mojgan; Giuriato, Sylvie; Tschan, Mario; Humbert, Magali (2019). Therapeutic Modulation of Autophagy in Leukaemia and Lymphoma. Cells, 8(2) MDPI 10.3390/cells8020103

2018

Janser, Ariane Félice; Adams, Olivia Joan; Bütler, Vanessa; Bill, Anna Magdalena; Dislich, Bastian; Seiler, Christian A.; Kröll, Dino; Langer, Rupert; Tschan, Mario (2018). Her2-Targeted Therapy Induces Autophagy in Esophageal Adenocarcinoma Cells. International journal of molecular sciences, 19(10) Molecular Diversity Preservation International MDPI 10.3390/ijms19103069

Graule, Janina; Uth-Gottardi, Kristin; Fischer, Elia Luca; Centeno Ramos, Irene; Galván Hernández, José Alberto; Eichmann, Micha David; Rau, Tilman; Langer, Rupert; Dawson, Heather; Nitsche, Ulrich; Traeger, Peter; Berger, Martin Dave; Schnüriger, Beat; Hädrich, Marion; Studer, Peter; Inderbitzin, Daniel; Lugli, Alessandro; Tschan, Mario; Zlobec, Inti (2018). CDX2 in colorectal cancer is an independent prognostic factor and regulated by promoter methylation and histone deacetylation in tumors of the serrated pathway. Clinical epigenetics, 10(1), p. 120. Springer 10.1186/s13148-018-0548-2

Niklaus, Nicolas Jan; Humbert, Magali; Tschan, Mario (2018). Cisplatin sensitivity in breast cancer cells is associated with particular DMTF1 splice variant expression. Biochemical and biophysical research communications, 503(4), pp. 2800-2806. Academic Press 10.1016/j.bbrc.2018.08.042

Jin, Jing; Britschgi, Adrian; Schläfli, Anna M.; Humbert, Magali; Shan-Krauer, Deborah; Batliner, Jasmin; Federzoni, Elena A.; Ernst, Marion; Torbett, Bruce E.; Yousefi, Shida; Simon, Hans-Uwe; Tschan, Mario (2018). Low Autophagy (ATG) Gene Expression Is Associated with an Immature AML Blast Cell Phenotype and Can Be Restored during AML Differentiation Therapy. Oxidative medicine and cellular longevity, 2018, p. 1482795. Hindawi 10.1155/2018/1482795

Adams, Olivia Joan; Janser, Ariane Félice; Dislich, Bastian; Berezowska, Sabina Anna; Humbert, Magali; Seiler, Christian A.; Kröll, Dino; Slotta-Huspenina, Julia; Feith, Marcus; Ott, Katja; Tschan, Mario; Langer, Rupert (2018). A specific expression profile of LC3B and p62 is associated with nonresponse to neoadjuvant chemotherapy in esophageal adenocarcinomas. PLoS ONE, 13(6), e0197610. Public Library of Science 10.1371/journal.pone.0197610

Langer, Rupert; Neppl, Christina; Keller, Manuel; Schmid, Ralph; Tschan, Mario; Berezowska, Sabina Anna (2018). Expression Analysis of Autophagy Related Markers LC3B, p62 and HMGB1 Indicate an Autophagy-Independent Negative Prognostic Impact of High p62 Expression in Pulmonary Squamous Cell Carcinomas. Cancers, 10(9), p. 281. MDPI AG 10.3390/cancers10090281

2017

Humbert, Magali; Federzoni, Elena; Tschan, Mario (2017). Distinct TP73-DAPK2-ATG5 pathway involvement in ATO-mediated cell death versus ATRA-mediated autophagy responses in APL. Journal of leukocyte biology, 102(6), pp. 1357-1370. Society for Leukocyte Biology 10.1189/jlb.1A0317-132R

Wiedmer, Tabea; Blank, Annika; Pantasis, Sophia; Normand, Lea Elena Haaning; Bill, Ruben; Krebs, Philippe; Tschan, Mario; Marinoni, Ilaria; Perren, Aurel (2017). Autophagy inhibition improves sunitinib efficacy in pancreatic neuroendocrine tumors via a lysosome-dependent mechanism. Molecular cancer therapeutics, 16(11), pp. 2502-2515. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-17-0136

Schläfli, Anna; Isakson, Pauline; Garattini, E; Simonsen, Anne; Tschan, Mario (2017). The autophagy scaffold protein ALFY is critical for the granulocytic differentiation of AML cells. Scientific Reports, 7(1), p. 12980. Nature Publishing Group 10.1038/s41598-017-12734-4

Niklaus, Monique; Adams, Olivia Joan; Berezowska, Sabina Anna; Zlobec, Inti; Graber, Franziska; Slotta-Huspenina, Julia; Nitsche, Ulrich; Rosenberg, Robert; Tschan, Mario; Langer, Rupert (2017). Expression analysis of LC3B and p62 indicates intact activated autophagy is associated with an unfavorable prognosis in colon cancer. OncoTarget, 8(33), pp. 54604-54615. Impact Journals LLC 10.18632/oncotarget.17554

Bakula, Daniela; Müller, Amelie J; Zuleger, Theresia; Takacs, Zsuzsanna; Franz-Wachtel, Mirita; Thost, Ann-Katrin; Brigger, Daniel; Tschan, Mario; Frickey, Tancred; Robenek, Horst; Macek, Boris; Proikas-Cezanne, Tassula (2017). WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy. Nature communications, 8(15637), p. 15637. Nature Publishing Group 10.1038/ncomms15637

Rothschild, Sacha; Gautschi, Oliver; Batliner, Jasmin; Gugger, Mathias; Fey, Martin; Tschan, Mario (2017). MicroRNA-106a targets autophagy and enhances sensitivity of lung cancer cells to Src inhibitors. Lung cancer, 107, pp. 73-83. Elsevier 10.1016/j.lungcan.2016.06.004

Haimovici, Aladin; Humbert, Magali; Federzoni, Elena A; Shan-Krauer, Deborah; Brunner, Thomas; Frese, Steffen; Kaufmann, Thomas; Torbett, Bruce E; Tschan, Mario (2017). PU.1 supports TRAIL-induced cell death by inhibiting NF-κB-mediated cell survival and inducing DR5 expression. Cell death and differentiation, 24(5), pp. 866-877. Nature Publishing Group 10.1038/cdd.2017.40

2016

Langsch, Stephanie; Baumgartner, Ulrich; Haemmig, Stefan; Schlup, Cornelia; Schäfer, Stephan; Berezowska, Sabina Anna; Rieger, Gregor; Dorn, Patrick; Tschan, Mario; Vassella, Erik (2016). miR-29b Mediates NF-κB Signaling in KRAS-Induced Non-Small Cell Lung Cancers. Cancer research, 76(14), pp. 4160-4169. American Association for Cancer Research AACR 10.1158/0008-5472.CAN-15-2580

Adams, Olivia Joan; Dislich, Bastian; Berezowska, Sabina Anna; Schläfli, Anna; Seiler, Christian A.; Kröll, Dino; Tschan, Mario; Langer, Rupert (2016). Prognostic relevance of autophagy markers LC3B and p62 in esophageal adenocarcinomas. OncoTarget, 7(26), pp. 39241-39255. Impact Journals LLC 10.18632/oncotarget.9649

Schläfli, Anna; Adams, Olivia Joan; Galván Hernández, José Alberto; Gugger, Mathias; Savic Prince, Spasenija; Bubendorf, Lukas; Schmid, Ralph; Becker, Karl-Friedrich; Tschan, Mario; Langer, Rupert; Berezowska, Sabina Anna (2016). Prognostic value of the autophagy markers LC3 and p62/SQSTM1 in early-stage non-small cell lung cancer. OncoTarget, 7(26), pp. 39544-39555. Impact Journals LLC 10.18632/oncotarget.9647

Weber, Martin R; Zuka, Masahiko; Lorger, Mihaela; Tschan, Mario; Torbett, Bruce E; Zijlstra, Andries; Quigley, James P; Staflin, Karin; Eliceiri, Brian P; Krueger, Joseph S; Marchese, Patrizia; Ruggeri, Zaverio M; Felding, Brunhilde H (2016). Activated tumor cell integrin αvβ3 cooperates with platelets to promote extravasation and metastasis from the blood stream. Thrombosis research, 140(Suppl1), S27-36. Elsevier 10.1016/S0049-3848(16)30095-0

Berezowska, Sabina Anna; Schläfli, Anna; Adams, O; Galván Hernández, José Alberto; Bubendorf, L; Prince, S Savic; Schmid, Ralph; Gugger, M; Tschan, Mario; Langer, Rupert (2016). 25P Autophagy in early stage NSCLC - prognostic significance of the autophagy markers p62 and LC3B. Journal of thoracic oncology, 11(4Suppl), S66-S66. Elsevier 10.1016/S1556-0864(16)30139-3

Wampfler, Julian; Federzoni, Elena; Torbett, Bruce E; Fey, Martin; Tschan, Mario (2016). The RNA binding proteins RBM38 and DND1 are repressed in AML and have a novel function in APL differentiation. Leukemia research, 41, pp. 96-102. Elsevier 10.1016/j.leukres.2015.12.006

Simon, Hans-Uwe; Tschan, Mario P.; Bütikofer, Peter (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 12(1), pp. 1-222. Landes Bioscience 10.1080/15548627.2015.1100356

2015

Mikami, K.; Medova, Michaela; Nisa Hernandez, Lluis; Francica, Paola; Glück, Astrid Andreina; Tschan, Mario; Blaukat, A.; Bladt, F.; Aebersold, Daniel; Zimmer, Yitzhak (2015). Impact of p53 Status on Radiosensitization of Tumor Cells by MET Inhibition-Associated Checkpoint Abrogation. Molecular cancer research, 13(12), pp. 1544-1553. American Association for Cancer Research AACR 10.1158/1541-7786.MCR-15-0022

Tschan, Mario P.; Federzoni, Elena A.; Haimovici, Aladin; Britschgi, Christian; Moser, Bettina A.; Jin, Jing; Reddy, Venkateshwar A.; Sheeter, Dennis A.; Fischer, Kimberlee M.; Sun, Peiqing; Torbett, Bruce E. (2015). Human DMTF1β antagonizes DMTF1α regulation of the p14(ARF) tumor suppressor and promotes cellular proliferation. Biochimica et biophysica acta - gene regulatory mechanisms, 1849(9), pp. 1198-1208. Elsevier 10.1016/j.bbagrm.2015.07.009

Wampfler, Julian; Federzoni, Elena; Torbett, Bruce E; Fey, Martin; Tschan, Mario (2015). Low DICER1 expression is associated with attenuated neutrophil differentiation and autophagy of NB4 APL cells. Journal of leukocyte biology, 98(3), pp. 357-363. Society for Leukocyte Biology 10.1189/jlb.1AB0514-258R

Orfali, Nina; O'Donovan, Tracey R; Nyhan, Michelle J; Britschgi, Adrian; Tschan, Mario; Cahill, Mary R; Mongan, Nigel P; Gudas, Lorraine J; McKenna, Sharon L (2015). Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic modulation. Experimental hematology, 43(9), 781-793.e2. Elsevier 10.1016/j.exphem.2015.04.012

Delgado Tascón, Julia; Adrian, Jonas; Kopp, Kathrin; Scholz, Philipp; Tschan, Mario; Kuespert, Katharina; Hauck, Christof R (2015). The granulocyte orphan receptor CEACAM4 is able to trigger phagocytosis of bacteria. Journal of leukocyte biology, 97(3), pp. 521-531. Society for Leukocyte Biology 10.1189/jlb.2AB0813-449RR

Galván Hernández, José Alberto; Helbling, Melina; Kölzer, Viktor; Tschan, Mario; Berger, Martin Dave; Hädrich, Marion; Schnüriger, Beat; Karamitopoulou, Evanthia; Dawson, Heather; Inderbitzin, Daniel; Lugli, Alessandro; Zlobec, Inti (2015). TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelial-mesenchymal transition-like tumor budding phenotype in colorectal cancer. OncoTarget, 6(2), pp. 874-885. Impact Journals LLC 10.18632/oncotarget.2716

Federzoni, Elena; Gloor, Severin; Jin, Jing; Krauer, Deborah; Fey, Martin; Torbett, Bruce E; Tschan, Mario (2015). Linking the SUMO protease SENP5 to neutrophil differentiation of AML cells. Leukemia research reports, 4(1), pp. 32-35. Elsevier 10.1016/j.lrr.2015.04.002

Brockmann, Anette; Bluwstein, A; Kögel, A; May, S; Marx, A; Tschan, Mario; Brunner, Thomas (2015). Thiazolides promote apoptosis in colorectal tumor cells via MAP kinase-induced Bim and Puma activation. Cell death & disease, 6, e1778. Nature Publishing Group 10.1038/cddis.2015.137

Schläfli, Anna; Berezowska, Sabina Anna; Adams, Olivia Joan; Langer, Rupert; Tschan, Mario (2015). Reliable LC3 and p62 autophagy marker detection in formalin fixed paraffin embedded human tissue by immunohistochemistry. European journal of histochemistry, 59(2), p. 2481. Luigi Ponzio 10.4081/ejh.2015.2481

Brigger, D.; Schläfli, Anna; Garattini, E.; Tschan, M. P. (2015). Activation of RARα induces autophagy in SKBR3 breast cancer cells and depletion of key autophagy genes enhances ATRA toxicity. Cell death & disease, 6(e1861), e1861. Nature Publishing Group 10.1038/cddis.2015.236

Geering, Barbara; Zokouri, Zina; Hürlemann, Samuel; Gerrits, Bertran; Ausländer, David; Britschgi, Adrian; Tschan, Mario; Simon, Hans-Uwe; Fussenegger, Martin (2015). Identification of Novel Death-Associated Protein Kinase 2 Interaction Partners by Proteomic Screening Coupled with Bimolecular Fluorescence Complementation. Molecular and cellular biology, 36(1), pp. 132-143. American Society for Microbiology 10.1128/MCB.00515-15

2014

Trocoli, A; Bensadoun, P; Richard, E; Labrunie, G; Merhi, F; Schläfli, Anna; Brigger, Daniel; Souquere, S; Pierron, G; Pasquet, J-M; Soubeyran, P; Reiffers, J; Ségal-Bendirdjian, E; Tschan, Mario; Djavaheri-Mergny, M (2014). p62/SQSTM1 upregulation constitutes a survival mechanism that occurs during granulocytic differentiation of acute myeloid leukemia cells. Cell death and differentiation, 21(12), pp. 1852-1861. Nature Publishing Group 10.1038/cdd.2014.102

Haimovici, Aladin; Brigger, Daniel; Torbett, Bruce E; Fey, Martin; Tschan, Mario (2014). Induction of the autophagy-associated gene MAP1S via PU.1 supports APL differentiation. Leukemia research, 38(9), pp. 1041-1047. Elsevier 10.1016/j.leukres.2014.06.010

Helbling, Melina; Lukesch, Anne Carolin; Haimovici, Aladin; Karamitopoulou, Evanthia; Berger, Martin Dave; Hädrich, Marion; Mallaev, Makhmud; Schnüriger, Beat; Kölzer, Viktor; Dawson, Heather; Borner, Markus; Langer, Rupert; Rosenberg, Robert; Nitsche, Ulrich; Inderbitzin, Daniel; Lugli, Alessandro; Tschan, Mario; Zlobec, Inti (2014). Investigation of IL-23 (p19, p40) and IL-23R identifies nuclear expression of IL-23 p19 as a favorable prognostic factor in colorectal cancer: a retrospective multicenter study of 675 patients. OncoTarget, 5(13), pp. 4671-4682. Impact Journals LLC

Pfisterer, Simon G; Bakula, Daniela; Frickey, Tancred; Cezanne, Alice; Brigger, Daniel; Tschan, Mario; Robenek, Horst; Proikas-Cezanne, Tassula (2014). Lipid droplet and early autophagosomal membrane targeting of Atg2A and Atg14L in human tumor cells. Journal of lipid research, 55(7), pp. 1267-1278. American Society for Biochemistry and Molecular Biology ASBMB 10.1194/jlr.M046359

Stutz, Emanuel; Gautschi, Oliver; Fey, Martin F.; Gugger, Mathias; Tschan, Mario; Rothschild, Sacha I. (2014). Crizotinib inhibits migration and expression of ID1 in MET-positive lung cancer cells: implications for MET targeting in oncology. Future oncology, 10(2), pp. 211-217. Future Medicine Ltd. 10.2217/fon.13.179

Humbert, Magali; Federzoni, Elena; Britschgi, Adrian; Schläfli, Anna; Valk, PJ; Kaufmann, Thomas; Haferlach, T.; Behre, G.; Simon, Hans-Uwe; Torbett, BE; Fey, Martin; Tschan, Mario (2014). The tumor suppressor gene DAPK2 is induced by the myeloid transcription factors PU.1 and C/EBPα during granulocytic differentiation but repressed by PML-RARα in APL. Journal of leukocyte biology, 95(1), pp. 83-93. Society for Leukocyte Biology 10.1189/jlb.1112608

Federzoni, Elena; Humbert, Magali; Torbett, Bruce E; Behre, Gerhard; Fey, Martin; Tschan, Mario (2014). CEBPA-dependent HK3 and KLF5 expression in primary AML and during AML differentiation. Scientific Reports, 4, p. 4261. Nature Publishing Group 10.1038/srep04261

Brigger, Daniel; Proikas-Cezanne, T; Tschan, Mario (2014). WIPI-dependent autophagy during neutrophil differentiation of NB4 acute promyelocytic leukemia cells. Cell death & disease, 5(e1315), e1315. Nature Publishing Group 10.1038/cddis.2014.261

Haemmig, Stefan; Baumgartner, Ulrich; Glück, Astrid; Zbinden, Samuel; Tschan, Mario; Kappeler, Andreas; Mariani, L; Vajtai, Istvan; Vassella, Erik (2014). miR-125b controls apoptosis and temozolomide resistance by targeting TNFAIP3 and NKIRAS2 in glioblastomas. Cell death & disease, 5(e1279), e1279. Nature Publishing Group 10.1038/cddis.2014.245

2013

Portmann, Simone; Fahrner, René; Lechleiter, Antje; Keogh, Adrian; Overney, Sarah; Lämmle, Alexander; Mikami, Kei; Montani, Matteo; Tschan, Mario; Candinas, Daniel; Keogh-Stroka, Deborah M. (2013). Antitumor effect of SIRT1 inhibition in human HCC tumor models in vitro and in vivo. Molecular cancer therapeutics, 12(4), pp. 499-508. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-12-0700

Humbert, Magali; Medova, Michaela; Aebersold, Daniel; Blaukat, Andree; Bladt, Friedhelm; Fey, Martin; Zimmer, Yitzhak; Tschan, Mario P. (2013). Protective autophagy is involved in resistance towards MET inhibitors in human gastric adenocarcinoma cells. Biochemical and biophysical research communications, 431(2), pp. 264-269. Academic Press 10.1016/j.bbrc.2012.12.120

Federzoni, Elena A.; Humbert, Magali; Valk, Peter J. M.; Behre, Gerhard; Leibundgut, Elisabeth O.; Torbett, Bruce E; Fey, Martin F.; Tschan, Mario (2013). The actin-binding protein CORO1A is a novel PU.1 (SPI1)- and CEBPA-regulated gene with significantly lower expression in APL and CEBPA-mutated AML patients. British journal of haematology, 160(6), pp. 855-859. Oxford: Wiley-Blackwell 10.1111/bjh.12170

Wojtalla, Anna; Fischer, Barbara; Kotelevets, Nataliya; Mauri, Francesco A; Sobek, Jens; Rehrauer, Hubert; Wotzkow, Carlos; Tschan, Mario P; Seckl, Michael J; Zangemeister-Wittke, Uwe; Arcaro, Alexandre (2013). Targeting the phosphoinositide 3-kinase p110-α isoform impairs cell proliferation, survival, and tumor growth in small cell lung cancer. Clinical cancer research, 19(1), pp. 96-105. Philadelphia, Pa.: American Association for Cancer Research 10.1158/1078-0432.CCR-12-1138

He, Zhaoyue; Liu, He; Agostini, M.; Yousefi, Shida; Perren, Aurel; Tschan, Mario; Mak, TW; Melino, G:; Simon, Hans-Uwe (2013). p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene. Cell death and differentiation, 20(10), pp. 1415-1424. Nature Publishing Group 10.1038/cdd.2013.104

Brigger, Daniel; Torbett, Bruce E.; Chen, Joy; Fey, Martin; Tschan, Mario (2013). Inhibition of GATE-16 attenuates ATRA-induced neutrophil differentiation of APL cells and interferes with autophagosome formation. Biochemical and biophysical research communications, 438(2), pp. 283-288. Academic Press 10.1016/j.bbrc.2013.07.056

2012

Batliner, Jasmin; Buehrer, Emanuel; Federzoni, Elena A; Jenal, Mathias; Tobler, Andreas; Torbett, Bruce E; Fey, Martin F; Tschan, Mario P (2012). Transcriptional regulation of MIR29B by PU.1 (SPI1) and MYC during neutrophil differentiation of acute promyelocytic leukaemia cells. British journal of haematology, 157(2), pp. 270-274. Oxford: Wiley-Blackwell 10.1111/j.1365-2141.2011.08964.x

Batliner, Jasmin; Buehrer, Emanuel; Fey, Martin F; Tschan, Mario P (2012). Inhibition of the miR-143/145 cluster attenuated neutrophil differentiation of APL cells. Leukemia research, 36(2), pp. 237-40. Amsterdam: Elsevier 10.1016/j.leukres.2011.10.006

Laemmle, Alexander; Lechleiter, Antje; Roh, Vincent; Schwarz, Christa; Portmann, Simone; Furer, Cynthia; Keogh, Adrian; Tschan, Mario P; Candinas, Daniel; Vorburger, Stephan A; Stroka, Deborah (2012). Inhibition of SIRT1 Impairs the Accumulation and Transcriptional Activity of HIF-1α Protein under Hypoxic Conditions. PLoS ONE, 7(3), e33433. Lawrence, Kans.: Public Library of Science 10.1371/journal.pone.0033433

Rothschild, S I; Tschan, M P; Federzoni, E A; Jaggi, R; Fey, M F; Gugger, M; Gautschi, O (2012). MicroRNA-29b is involved in the Src-ID1 signaling pathway and is dysregulated in human lung adenocarcinoma. Oncogene, 31(38), pp. 4221-32. Basingstoke, UK: Nature Publishing Group 10.1038/onc.2011.578

Rothschild, Sacha I; Tschan, Mario P; Jaggi, Rolf; Fey, Martin F; Gugger, Mathias; Gautschi, Oliver (2012). MicroRNA-381 Represses ID1 and is Deregulated in Lung Adenocarcinoma. Journal of thoracic oncology, 7(7), pp. 1069-77. Hagerstown, Md.: Wolters Kluwer Health/Lippincott Williams & Wilkins 10.1097/JTO.0b013e31824fe976

Federzoni, Elena A; Valk, Peter J M; Torbett, Bruce E; Haferlach, Torsten; Löwenberg, Bob; Fey, Martin F; Tschan, Mario P (2012). PU.1 is linking the glycolytic enzyme HK3 in neutrophil differentiation and survival of APL cells. Blood, 119(21), pp. 4963-70. Washington, D.C.: American Society of Hematology 10.1182/blood-2011-09-378117

Humbert, Magali; Mueller, Chantal; Fey, Martin F; Tschan, Mario P (2012). Inhibition of damage-regulated autophagy modulator-1 (DRAM-1) impairs neutrophil differentiation of NB4 APL cells. Leukemia research, 36(12), pp. 1552-6. Amsterdam: Elsevier 10.1016/j.leukres.2012.08.024

Yusuf, Dimas; Butland, Stefanie L; Swanson, Magdalena I; Bolotin, Eugene; Ticoll, Amy; Cheung, Warren A; Zhang, Xiao Yu Cindy; Dickman, Christopher T D; Fulton, Debra L; Lim, Jonathan S; Schnabl, Jake M; Ramos, Oscar H P; Vasseur-Cognet, Mireille; de Leeuw, Charles N; Simpson, Elizabeth M; Ryffel, Gerhart U; Lam, Eric W-F; Kist, Ralf; Wilson, Miranda S C; Marco-Ferreres, Raquel; ... (2012). The transcription factor encyclopedia. Genome biology, 13(3), R24. London: BioMed Central Ltd. 10.1186/gb-2012-13-3-r24

2011

Rothschild, Sacha I; Kappeler, Andreas; Ratschiller, Daniel; Betticher, Daniel C; Tschan, Mario P; Gugger, Mathias; Gautschi, Oliver (2011). The stem cell gene "inhibitor of differentiation 1" (ID1) is frequently expressed in non-small cell lung cancer. Lung cancer, 71(3), pp. 306-11. Amsterdam: Elsevier 10.1016/j.lungcan.2010.06.018

Batliner, Jasmin; Mancarelli, Maria Michela; Jenal, Mathias; Reddy, Venkateshwar A; Fey, Martin F; Torbett, Bruce E; Tschan, Mario P (2011). CLEC5A (MDL-1) is a novel PU.1 transcriptional target during myeloid differentiation. Molecular immunology, 48(4), pp. 714-9. Amsterdam: Elsevier 10.1016/j.molimm.2010.10.016

Humbert, Magali; Halter, Veronika; Shan, Deborah; Laedrach, Judith; Leibundgut, Elisabeth Oppliger; Baerlocher, Gabriela M; Tobler, Andreas; Fey, Martin F; Tschan, Mario P (2011). Deregulated expression of Kruppel-like factors in acute myeloid leukemia. Leukemia research, 35(7), pp. 909-13. Amsterdam: Elsevier 10.1016/j.leukres.2011.03.010

2010

Tschan, Mario P; Shan, Deborah; Laedrach, Judith; Eyholzer, Marianne; Leibundgut, Elisabeth Oppliger; Baerlocher, Gabriela M; Tobler, Andreas; Stroka, Deborah; Fey, Martin F (2010). NDRG1/2 expression is inhibited in primary acute myeloid leukemia. Leukemia research, 34(3), pp. 393-8. Amsterdam: Elsevier 10.1016/j.leukres.2009.08.037

Jenal, M; Batliner, J; Reddy, V A; Haferlach, T; Tobler, A; Fey, M F; Torbett, B E; Tschan, M P (2010). The anti-apoptotic gene BCL2A1 is a novel transcriptional target of PU.1. Leukemia, 24(5), pp. 1073-6. Basingstoke: Nature Publishing Group 10.1038/leu.2010.26

Britschgi, Adrian; Simon, Hans-Uwe; Tobler, Andreas; Fey, Martin F; Tschan, Mario P (2010). Epigallocatechin-3-gallate induces cell death in acute myeloid leukaemia cells and supports all-trans retinoic acid-induced neutrophil differentiation via death-associated protein kinase 2. British journal of haematology, 149(1), pp. 55-64. Oxford: Wiley-Blackwell 10.1111/j.1365-2141.2009.08040.x

Tschan, M P; Simon, H-U (2010). The role of autophagy in anticancer therapy: promises and uncertainties. Journal of internal medicine, 268(5), pp. 410-8. Oxford: Blackwell Scientific Publications 10.1111/j.1365-2796.2010.02266.x

Schneider-Jakob, S; Corazza, N; Badmann, A; Sidler, D; Stuber-Roos, R; Keogh, A; Frese, S; Tschan, M; Brunner, T (2010). Synergistic induction of cell death in liver tumor cells by TRAIL and chemotherapeutic drugs via the BH3-only proteins Bim and Bid. Cell death & disease, 1(e86), e86. London: Nature Publishing Group 10.1038/cddis.2010.66

Jenal, Mathias; Britschgi, Christian; Fey, Martin F; Tschan, Mario P (2010). Inactivation of the hypermethylated in cancer 1 tumour suppressor--not just a question of promoter hypermethylation? Swiss medical weekly, 140, w13106. Muttenz: EMH Schweizerischer Ärzteverlag 10.4414/smw.2011.13106

2009

Wampfler, Julian; Tschan, Mario P; Shan, Deborah; Laemmle, Alexander; Leibundgut, Elisabeth O; Baerlocher, Gabriela M; Stroka, Deborah; Fey, Martin F; Britschgi, Christian (2009). SIRT1 is downregulated during neutrophil differentiation of acute promyelocytic leukaemia cells. British journal of haematology, 146(3), pp. 337-41. Oxford: Wiley-Blackwell 10.1111/j.1365-2141.2009.07749.x

Jenal, Mathias; Trinh, Emmanuelle; Britschgi, Christian; Britschgi, Adrian; Roh, Vincent; Vorburger, Stephan A; Tobler, Andreas; Leprince, Dominique; Fey, Martin F; Helin, Kristian; Tschan, Mario P (2009). The tumor suppressor gene hypermethylated in cancer 1 is transcriptionally regulated by E2F1. Molecular cancer research, 7(6), pp. 916-22. Philadelphia, Pa.: American Association for Cancer Research AACR 10.1158/1541-7786.MCR-08-0359

Van Rechem, C.; Rood, B. R.; Touka, M.; Pinte, S.; Jenal, Mathias; Guerardel, C.; Ramsey, K.; Monte, D.; Begue, A.; Tschan, Mario; Stephan, D. A.; Leprince, D. (2009). Scavenger Chemokine (CXC Motif) Receptor 7 (CXCR7) Is a Direct Target Gene of HIC1 (Hypermethylated in Cancer 1). Journal of biological chemistry, 284(31), pp. 20927-20935. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M109.022350

2008

Britschgi, Christian; Jenal, Mathias; Rizzi, Mattia; Mueller, Beatrice U; Torbett, Bruce E; Andres, Anne-Catherine; Tobler, Andreas; Fey, Martin F; Tschan, Mario P (2008). HIC1 tumour suppressor gene is suppressed in acute myeloid leukaemia and induced during granulocytic differentiation. British journal of haematology, 141(2), pp. 179-87. Oxford: Wiley-Blackwell 10.1111/j.1365-2141.2008.06992.x

Tschan, M P; Reddy, V A; Ress, A; Arvidsson, G; Fey, M F; Torbett, B E (2008). PU.1 binding to the p53 family of tumor suppressors impairs their transcriptional activity. Oncogene, 27(24), pp. 3489-93. Basingstoke, UK: Nature Publishing Group 10.1038/sj.onc.1211004

Blancafort, P.; Tschan, Mario; Bergquist, S.; Guthy, D.; Brachat, A.; Sheeter, D. A.; Torbett, B. E.; Erdmann, D.; Barbas, C. F. (2008). Modulation of drug resistance by artificial transcription factors. Molecular cancer therapeutics, 7(3), pp. 688-697. American Association for Cancer Research AACR 10.1158/1535-7163.MCT-07-0381

Fang, J.; Menon, M.; Zhang, D.; Torbett, B.; Oxburgh, L.; Tschan, Mario; Houde, E.; Wojchowski, D. M. (2008). Attenuation of EPO-dependent erythroblast formation by death-associated protein kinase-2. Blood, 112(3), pp. 886-890. American Society of Hematology 10.1182/blood-2008-02-138909

2007

Tschan, M P; Gullberg, U; Shan, D; Torbett, B E; Fey, M F; Tobler, A (2007). The hDMP1 tumor suppressor is a new WT1 target in myeloid leukemias. Leukemia, 22(5), pp. 1087-1090. Basingstoke: Nature Publishing Group 10.1038/sj.leu.2405018

Swan, C H; Bühler, B; Steinberger, P; Tschan, Mario; Barbas, C F; Torbett, B E (2007). T-cell protection and enrichment through lentiviral CCR5 intrabody gene delivery. Gene therapy, 14(7), p. 626. Nature Publishing Group 10.1038/sj.gt.3302902

2003

Tschan, Mario; Fischer, K. M.; Fung, V. S.; Pirnia Borner, Farzaneh; Borner, Markus; Fey, Martin; Tobler, Andreas; Torbett, B. E. (2003). Alternative Splicing of the Human Cyclin D-binding Myb-like Protein (hDMP1) Yields a Truncated Protein Isoform That Alters Macrophage Differentiation Patterns. Journal of biological chemistry, 278(44), pp. 42750-42760. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M307067200

2001

Novak, Urban; Grob, T. J.; Baskaynak, G.; Peters, U. R.; Aebi, Stefan; Zwahlen, D.; Tschan, Mario; Kreuzer, K.-A.; Oppliger Leibundgut, Elisabeth; Cajot, J.-F.; Tobler, Andreas; Fey, Martin (2001). Overexpression of the p73 gene is a novel finding in high-risk B-cell chronic lymphocytic leukemia. Annals of oncology, 12(7), pp. 981-986. Oxford University Press 10.1023/A:1011153206003

2000

Tschan, Mario; Grob, Tobias J.; Peters, Uwe R.; Laurenzi, Vincenzo De; Huegli, B.; Kreuzer, K.-A.; Schmidt, C.A.; Melino, Gerry; Fey, Martin F.; Tobler, Andreas; Cajot, Jean-François (2000). Enhanced p73 Expression during Differentiation and Complex p73 Isoforms in Myeloid Leukemia. Biochemical and biophysical research communications, 277(1), pp. 62-65. Academic Press 10.1006/bbrc.2000.3627

Zwahlen, Daniel; Tschan, Mario; Grob, Tobias J.; Peters, Uwe R.; Fink, Daniel; Haenggi, Willy; Altermatt, Hans J.; Cajot, Jean-François; Tobler, Andreas; Fey, Martin F.; Aebi, Stefan (2000). Differential expression of p73 splice variants and protein in benign and malignant ovarian tumours. International journal of cancer, 88(1), pp. 66-70. Wiley-Blackwell 10.1002/1097-0215(20001001)88:1<66::AID-IJC10>3.0.CO;2-Y

1999

Tschan, Mario; Peters, U. R.; Cajot, J. F.; Betticher, D. C.; Fey, M. F.; Tobler, A. (1999). The cyclin-dependent kinase inhibitors p18INK4c and p19INK4d are highly expressed in CD34+ progenitor and acute myeloid leukaemic cells but not in normal differentiated myeloid cells. British journal of haematology, 106(3), pp. 644-651. Wiley-Blackwell 10.1046/j.1365-2141.1999.01617.x

Peters, Uwe R; Hasse, Urs; Oppliger Leibundgut, Elisabeth; Tschan, Mario; Ong, S Tiong; Rassool, Feyruz V; Borisch, Bettina; Tobler, Andreas; Fey, Martin (1999). Aberrant FHIT mRNA transcripts are present in malignant and normal haematopoiesis, but absence of FHIT protein is restricted to leukaemia. Oncogene, 18(1), pp. 79-85. Nature Publishing Group 10.1038/sj.onc.1202256